A new study suggests that treatment with stem cells from umbilical cord blood might be an effective therapy for patients with moderate-to-severe eczema, or atopic dermatitis.
For the clinical trial, 34 patients were randomly assigned to receive a low dose or high dose of the cells subcutaneously. Fifty five percent of patients who received the high dose showed a 50% reduction in what’s known as the Eczema Area and Severity Index score at week 12. Immune-related markers of atopic dermatitis also decreased significantly.
“This study is a first-in-class study demonstrating that adults with moderate-to-severe atopic dermatitis responded to a treatment of stem cells derived from umbilical cord blood,” said Dr. Tae-Yoon Kim, senior author of the Stem Cells study. “The single treatment of stem cells in patients resulted in the significant and persistent improvement in disease symptoms throughout the follow-up period of 12 weeks.”
The study was conducted at Seoul St. Mary’s Hospital in collaboration with Seoul National University (with co-senior author, Dr. Kyung-Sun Kang).
Bibliography
STEM CELLS
Hyung-Sik Kim1,†,‡,§, Ji Hyun Lee4,§, Kyoung-Hwan Roh5, Hee Jin Jun4, Kyung-Sun Kang1,5,¶,* and Tae-Yoon Kim4,¶,*
DOI: 10.1002/stem.2401
Source: Alpha Galileo
Stem Cells from Umbilical Cord Blood May Help Treat Eczema
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