New Results Demonstrate that Findings from Large-Scale Prostate Cancer Treatment Research Study Have Been Properly Implemented

Researchers evaluated treatment trends at a large treatment center in Chicago following the publication of the results of PIVOT (The Prostate Intervention Versus Observation Trial), which showed that radical prostatectomy did not benefit men with favorable-risk prostate cancer.

Following the findings of PIVOT, researchers observed a drop in PSA screening in the United States and less treatment for all men with low risk prostate cancer.

In new research published in the European Urology Focus led by Stephen A. Mihalcik, MD, PhD, a physician and researcher in the Radiation Oncology Residency Program at Brigham and Women’s Hospital, investigators found that treatment dropped in men with favorable risk prostate cancer who had multiple comorbidities, but increased in men at high risk for having aggressive prostate cancer.

“Our findings show that the results of PIVOT have been effectively interpreted in the Chicago area,” said Mihalcik.  “This is important, as there have been concerns raised that the results would be applied indiscriminately to all men.  We find that is not the case, but rather the results are appropriately applied to those in less than average health and those not at high risk.”

Researchers note that further research is necessary to determine if the observations seen in these data can be generalized to larger populations.

If you’re interested in learning more, I’m happy to provide full text of the study and Dr. Mihalcik is available to further discuss the findings.

Lori J. Schroth
Manager, Media Relations, Communication & Public Affairs
Brigham and Women's Hospital
(office) 617.525.6374
(cell) 617.459.2111

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New Results Demonstrate that Findings from Large-Scale Prostate Cancer Treatment Research Study Have Been Properly Implemented